Vice President, Translational Medicine Greater San Francisco, CA Area

The Company is seeking a Vice President of Translational Medicine to shape and execute translational strategy across its portfolio. The role will connect disease mechanisms with human biology evidence, biomarker strategies, and clinical development decisions, while leading translational planning and execution across programs. Responsibilities include building and guiding a multidisciplinary team, developing biomarker and assay strategies, integrating clinical, imaging, and omics data, and applying computational methods to support evidence-based decisions. The VP will also collaborate across scientific and clinical functions, contribute to regulatory and scientific communications, and develop external research partnerships. Candidates must hold an MD, PhD, or MD/PhD and have at least 15 years of relevant pharmaceutical or biotechnology experience, including leadership in translational medicine, biomarkers, or clinical development. Required expertise includes building translational organizations and bioinformatics capabilities, applying machine learning and advanced computational methods, and using observational, natural history, or real-world data. Deep experience in at least one relevant therapeutic area, such as neurology, ophthalmology, or immunology, is required, along with strong knowledge of biomarker strategy, assay development, clinical sample operations, and quantitative data integration. Candidates should also bring regulatory collaboration experience, strong communication and leadership skills, and strategic business judgment.

Hiring Company

Annexon, Inc.