Head of Clinical Pharmacology

The Company is in search of a Head of Clinical Pharmacology to spearhead the strategic development of next-generation biologics and breakthrough therapies. The successful candidate will be responsible for shaping and leading clinical pharmacology and pharmacodynamics strategies, with a focus on advancing innovative therapies in oncology and immunology from First-in-Human studies to regulatory approval. This pivotal role involves collaboration with cross-functional teams, driving global development programs, and overseeing the design and execution of FIH studies, dose-escalation strategies, and PK-PD assessments. Applicants for the Head of Clinical Pharmacology position at the company should possess an advanced degree in a relevant field and have a strong background in biologics development, including a proven track record with multiple FIH programs. Expertise in FDA interactions, particularly in BLA submissions, and leadership experience in managing a PD or clinical pharmacology team are essential. The role also requires proficiency in PK-PD, dose optimization, and global clinical development, with a preference for candidates who have experience with innovative biologics and a deep understanding of FDA regulatory requirements. The Head of Clinical Pharmacology will be at the forefront of scientific guidance, providing input on PK-PD modeling, exposure-response analysis, and dose selection, and will play a key role in advancing global development programs through collaboration with clinical, regulatory, and cross-functional teams.